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Meridian Biologics has experience with the production of recombinant proteins using microbial fermentation for Research and Development projects and for the production of Biopharmaceutical products under cGMPs. Meridian Biologics Fermentation capabilities are as follows
| Microbial Fermentation |
Y |
Total Capacity in L = 65 BioFlo Pro Steel Tank |
Add 10-20L Fermentor |
Recombinant proteins and bacterial antigens. |
Meridian Biologics ancillary biomanufacturing services include:
Cell Line Development/
Expression Systems:
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Seamless tech transfer from development to clinical production. |
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Reduced production cost via development of optimal high yield microbial cell lines or plasmids. |
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Cloning strategy and expression system development for high-level production of active, functional proteins. |
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Selection of optimal clones and expression systems. |
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| Cell Banking: |
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Bacterial: cGMP master and working E. coli bank for use in the production of a recombinant Chagas antigen for use in blood bank diagnostics and early stage biopharmaceutical recombinant proteins. |
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| Fermentation Equipment: |
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Shaker flask. |
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Stainless Tank Fermentor: 75 Liter New Brunswick BioFlo Pro fermentor, (60 Liter, cGMP). |
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cGMP Fermentation